![]() What makes the vital layer of protective cells around the brain and spinal cord - the blood-brain barrier - more or less permeable has been one of the more mystifying questions in neuroscience. The findings could help scientists control the blood-brain barrier - important for delivering drugs into the central nervous system or countering damage from neurodegenerative disease.When mutated, the gene makes certain regions of the blood-brain barrier more permeable.Working with mice and zebrafish, researchers identify a gene, expressed in neurons, that produces a signal needed for development and maintenance of the blood-brain barrier.Harvard COVID-19 Information: Keep Harvard Healthy.Research Departments, Centers, Initiatives and more.
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